Top 5 Takeaways Vaccine Effectiveness: Moderna’s vaccine was 86% effective and Pfizer-BioNTech’s was 75% effective in preventing COVID-19–associated hospitalizations ≥120 days after the second dose. Antibody Levels: Antibody responses to

Top 5 Takeaways Sharp Increase in Deaths: IMF-involved overdose deaths surged in midwestern (33.1%), southern (64.7%), and western (93.9%) regions during 2019-2020. Polysubstance Use: Approximately 40% of IMF-involved deaths also

Top 5 Takeaways High Booster Uptake: 18.7 million adults aged ≥65 years received a booster or additional primary dose, representing 44.1% of eligible individuals in this age group. Coverage Variation:

Top 5 Takeaways Provider Recommendations Increase Vaccination Rates: Adults who received a COVID-19 vaccination recommendation from a health care provider were more likely to have been vaccinated (77.6%) compared to