Top 5 Takeaways Emerging Substance: Xylazine, a veterinary tranquilizer, is increasingly found in drug overdose deaths in Connecticut. Combination with Fentanyl: Nearly all xylazine-positive deaths also involved fentanyl, highlighting a

Top 5 Takeaways High Adverse Event Rate: 91.4% of patients reported experiencing at least one adverse event during treatment with nifurtimox. Demographic Concentration: Most patients were adults aged ≥18 years

Top 5 Takeaways High Specificity: The study found that the specificity of DENV and SARS-CoV-2 enzyme-linked immunosorbent assays (ELISAs) was ≥98%, indicating minimal cross-reactivity. Minimal Cross-Reactivity: Results showed minimal levels

Top 5 Takeaways High Vaccine Effectiveness: COVID-19 mRNA vaccines were 86.8% effective in preventing COVID-19–associated hospitalization among U.S. veterans. Effectiveness Across Variants: The effectiveness remained high during both pre-Delta (84.1%)

Top 5 Takeaways High Overall Vaccine Effectiveness: COVID-19 vaccines showed high effectiveness against hospitalization (86%) and emergency department/urgent care (ED/UC) encounters (82%) during the Delta variant predominance. Age-Related Differences: Vaccine

Top 5 Takeaways Increased Hospitalization Rates: During the Omicron variant predominance, infants and children aged 0–4 years were hospitalized at approximately five times the rate compared to the Delta variant

Top 5 Takeaways Vaccine Effectiveness: The study found a potential decline in vaccine protection against confirmed SARS-CoV-2 infection but continued strong protection against COVID-19–associated hospitalization and death. Impact of Delta